STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0433Arginine/ornithine antiporter; Similar to GB:U00096 PID:1742644 PID:1742655 PID:1787890; identified by sequence similarity; putative. (468 aa)    
Predicted Functional Partners:
VC_0911
Trehalose-6-phosphate hydrolase; Similar to SP:P39795 PID:580942 PID:1000452 GB:AL009126; identified by sequence similarity; putative.
    
 0.877
VC_A0250
Alpha-amylase; Similar to PID:1177849; identified by sequence similarity; putative.
    
 0.877
VC_A0860
Alpha-amylase; Similar to SP:P25718 GB:X58994 PID:41966 PID:466709 GB:U00096; identified by sequence similarity; putative.
    
 0.877
arcA
Arginine deiminase; Similar to GB:X14694 SP:P13981 GB:S43866 PID:45286; identified by sequence similarity; putative.
 
  
 0.838
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.736
VC_0705
Chorismate mutase/prephenate dehydratase; Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390; identified by sequence similarity; putative.
   
 0.663
VC_A0067
Hypothetical protein; Identified by Glimmer2; putative.
    
 0.623
VC_1584
ankB protein; Similar to PID:563740 PID:1754534; identified by sequence similarity; putative.
   
 0.565
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
   
 0.554
trpCF
Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
    
 
 0.548
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: high (98%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.