Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_0433Arginine/ornithine antiporter; Similar to GB:U00096 PID:1742644 PID:1742655 PID:1787890; identified by sequence similarity; putative. (468 aa)    
Predicted Functional Partners:
arcA
Arginine deiminase; Similar to GB:X14694 SP:P13981 GB:S43866 PID:45286; identified by sequence similarity; putative.
 
  
 0.825
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.746
VC_0911
Trehalose-6-phosphate hydrolase; Similar to SP:P39795 PID:580942 PID:1000452 GB:AL009126; identified by sequence similarity; putative.
    
 0.694
VC_A0250
Alpha-amylase; Similar to PID:1177849; identified by sequence similarity; putative.
    
 0.694
VC_A0860
Alpha-amylase; Similar to SP:P25718 GB:X58994 PID:41966 PID:466709 GB:U00096; identified by sequence similarity; putative.
    
 0.694
VC_A0067
Hypothetical protein; Identified by Glimmer2; putative.
    
 0.588
trpCF
Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
    
 
 0.570
VC_A0686
iron(III) ABC transporter, permease protein; Similar to PID:1469285 PID:1477454; identified by sequence similarity; putative.
      
 0.540
VC_A0955
Transcriptional regulator, MarR family; Similar to GB:X74409 SP:P42195 PID:396458; identified by sequence similarity; putative.
      
 0.531
VC_A0847
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.433
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.