Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0463Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative. (368 aa)    
Predicted Functional Partners:
VC_0462
Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative.
 
  
0.889
VC_2634
Fimbrial assembly protein PilM, putative; Similar to GB:L28837 PID:895925; identified by sequence similarity; putative.
  
  
 0.882
tcpJ
Leader peptidase TcpJ; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. Processes the TcpA pilin precursor during membrane translocation.
  
   
 0.827
VC_2426
Leader peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
   
 0.815
pilC
Type IV pilin biogenesis protein PilC; Involved in the translocation of the type IV pilin; Belongs to the GSP F family.
 
   
 0.811
VC_0406
MSHA biogenesis protein MshG; Similar to PID:1016255 PID:1016256; identified by sequence similarity; putative.
 
   
 0.809
VC_2630
Fimbrial assembly protein; Similar to GB:L13865 SP:P34750 PID:459551; identified by sequence similarity; putative.
  
  
 0.806
epsF
General secretion pathway protein F; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
 
   
 0.787
VC_0461
Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
       0.746
VC_2633
Fimbrial assembly protein PilN, putative; Similar to GB:U12892 PID:530857; identified by sequence similarity; putative.
  
  
 0.708
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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