Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0464Transcriptional regulator, LuxR family; Similar to GB:X80506 SP:P45785 PID:516862; identified by sequence similarity; putative. (267 aa)    
Predicted Functional Partners:
VC_2453
Sensor histidine kinase/response regulator; Similar to GB:D10888 SP:P26607 PID:216535 PID:882680 GB:U00096; identified by sequence similarity; putative.
   
 
 0.860
VC_1653
Sensory box sensor histidine kinase/response regulator VieS; Similar to GP:3123890; identified by sequence similarity; putative.
   
 
 0.857
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
   
 
 0.815
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
   
 
 0.815
VC_A0709
Sensor protein TorS; Similar to SP:P39453 PID:1122856 GB:U00096 PID:1787227; identified by sequence similarity; putative.
   
 
 0.789
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
   
 
 0.730
tyrS1
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
 
     0.636
VC_1367
GGDEF family protein; Similar to PID:633121; identified by sequence similarity; putative.
  
 
 0.630
VC_1445
Sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
   
 
 0.626
VC_1831
Sensor histidine kinase; Similar to GB:U07069 PID:459205 SP:P54302; identified by sequence similarity; putative.
   
 
 0.626
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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