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VC_0467 protein (Vibrio cholerae O1) - STRING interaction network
"VC_0467" - UPF0301 protein VC_0467 in Vibrio cholerae O1
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co-expression
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VC_0467UPF0301 protein VC_0467; Identified by Glimmer2; putative; Belongs to the UPF0301 (AlgH) family (200 aa)    
Predicted Functional Partners:
VC_1256
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (761 aa)
     
 
  0.938
VC_0466
Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5’-end of pre-16S rRNA (140 aa)
   
   
  0.910
gshB
Glutathione synthetase; Similar to SP-P04425 GB-X01666 PID-41625 PID-882476 GB-U00096; identified by sequence similarity; putative (318 aa)
 
        0.905
VC_0469
Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (243 aa)
   
      0.888
dnaN
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (366 aa)
   
   
  0.887
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis (283 aa)
     
 
  0.846
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids; Belongs to the RNase HII family (206 aa)
   
        0.741
der
GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis (494 aa)
           
  0.707
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (934 aa)
 
   
  0.679
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (142 aa)
   
   
  0.598
Your Current Organism:
Vibrio cholerae O1
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1, Vibrio cholerae O1 biovar, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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