Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tkt1Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (694 aa)    
Predicted Functional Partners:
tal
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.993
VC_2625
Ribulose-phosphate 3-epimerase; Similar to SP:P32661 GB:Z19601 PID:41222 GB:U00096 PID:1789788; identified by sequence similarity; putative; Belongs to the ribulose-phosphate 3-epimerase family.
 0.985
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.983
pgi
Glucose-6-phosphate isomerase; Similar to SP:P11537 GB:X15196 PID:396360 PID:42377 GB:U00096; identified by sequence similarity; putative.
  
 0.976
VC_0478
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.967
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 0.959
VC_2000
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:X02662 SP:P06977 GB:M66870 GB:M66871 GB:M66872; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.958
VC_A0843
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GP:3170587; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.957
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.956
fbp
Fructose-1,6-bisphosphatase; Similar to SP:P09200 GB:X12545 PID:41416 PID:537074 GB:U00096; identified by sequence similarity; putative.
  
 
 0.954
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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