Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_0552Quinone oxidoreductase; Similar to GP:3293547; identified by sequence similarity; putative. (337 aa)    
Predicted Functional Partners:
VC_0553
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_0554
Protease, insulinase family/protease, insulinase family; Similar to GP:2661690; identified by sequence similarity; putative.
  
    0.849
nqrB
NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrB; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
      
 0.824
nqrF
NADH:ubiquinone oxidoreductase, Na translocating, beta subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
      
 0.819
nqrC
NADH:ubiquinone oxidoreductase, Na translocating, gamma subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
      
 0.818
VC_0550
Oxaloacetate decarboxylase, alpha subunit; Similar to GB:J03885 SP:P13187 PID:149289; identified by sequence similarity; putative.
     
 0.785
gshA
Glutamate--cysteine ligase; Similar to SP:P06980 GB:X03954 PID:581100 GB:U00096 PID:1789044; identified by sequence similarity; putative; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.775
oadG1
Hypothetical protein; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
 
     0.772
nqrE
NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.
      
 0.726
nqrA
NADH:ubiquinone oxidoreductase, Na translocating, alpha subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
      
 0.724
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (30%) [HD]