STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase; Similar to SP:P06980 GB:X03954 PID:581100 GB:U00096 PID:1789044; identified by sequence similarity; putative; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (524 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Similar to SP:P04425 GB:X01666 PID:41625 PID:882476 GB:U00096; identified by sequence similarity; putative.
 
 
 0.917
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.741
glnAv
Glutamate--ammonia ligase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
     
 0.662
ddl
D-alanine--D-alanine ligase; Cell wall formation.
    
 0.657
VC_1494
Aminopeptidase N; Similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142; identified by sequence similarity; putative.
     
 0.652
VC_1671
Cystathionine beta-lyase; Similar to GB:M12858 SP:P06721 PID:146824 PID:882537 PID:1789383; identified by sequence similarity; putative.
     
 0.649
VC_0552
Quinone oxidoreductase; Similar to GP:3293547; identified by sequence similarity; putative.
     
 0.648
VC_2160
Bacterioferritin comigratory protein; Similar to GB:M63654 SP:P23480 PID:147017 GB:U00096 PID:1621502; identified by sequence similarity; putative.
     
 0.639
VC_2279
Aminoacyl-histidine dipeptidase; Similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140; identified by sequence similarity; putative.
   
 
 0.638
VC_0968
Cysteine synthase A; Similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.632
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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