STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_05932-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801; identified by sequence similarity; putative. (167 aa)    
Predicted Functional Partners:
VC_0638
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase; Similar to GB:U00007 SP:P27511 GB:X63910 PID:312964 PID:405902; identified by sequence similarity; putative.
  
 0.988
VC_0524
Dihydroneopterin aldolase FolB, putative; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.985
pcnB
polyA polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.946
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
 
 0.908
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
   
 0.875
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.862
VC_1001
Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GB:M68934 SP:P08192 GB:M32445 PID:146009 PID:146020; identified by sequence similarity; putative; Belongs to the folylpolyglutamate synthase family.
 
 
 0.852
VC_0525
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801; identified by sequence similarity; putative.
  
  
 
0.697
VC_1303
Para-aminobenzoate synthase, component I; Similar to GB:K02673 SP:P05041 GB:U07748 GB:U07749 GB:U07755; identified by sequence similarity; putative.
 
 
 0.682
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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