STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0605Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0231 family. (126 aa)    
Predicted Functional Partners:
VC_A0135
Cyclic nucleotide binding protein, putative; Similar to GB:AE000520; identified by sequence similarity; putative.
  
 
   0.843
VC_2614
Cyclic AMP receptor protein; Similar to GP:2580527; identified by sequence similarity; putative.
    
   0.800
VC_2563
Hypothetical protein; Identified by Glimmer2; putative.
  
 
   0.752
VC_2112
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.676
VC_1156
Sensor histidine kinase; Similar to GP:2655263; identified by sequence similarity; putative.
   
   0.664
VC_1157
Response regulator; Similar to PID:643672; identified by sequence similarity; putative.
   
   0.664
fnr
Fumarate and nitrate reduction regulatory protein; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
    
   0.664
VC_A0634
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.654
trpR
Trp operon repressor, putative; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity).
  
     0.555
VC_0606
Nitrogen regulatory protein P-II; Similar to GB:U00096 PID:1788904 PID:1799977; identified by sequence similarity; putative; Belongs to the P(II) protein family.
       0.537
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.