Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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gspKConserved hypothetical protein; ATP-dependent kinase, which is specific for glucosamine. Does not show kinase activity with any other sugar. Belongs to the eukaryotic-type N-acetylglucosamine kinase family. (325 aa)    
Predicted Functional Partners:
VC_1783
N-acetylglucosamine-6-phosphate deacetylase; Similar to SP:O32445; identified by sequence similarity; putative.
 
 
 0.959
nagA
N-acetylglucosamine-6-phosphate deacetylase; Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6- phosphate and acetate.
 
 
 0.954
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
  0.931
VC_0615
Endoglucanase-related protein; Similar to PID:1663519; identified by sequence similarity; putative.
 
     0.920
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.917
VC_0613
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
 
     0.910
glmM
Phosphoglucomutase/phosphomannomutase family protein MrsA; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.902
VC_0619
Peptide ABC transporter, permease protein; Similar to GB:Pyro_h; identified by sequence similarity; putative.
 
   
 0.869
VC_0620
Peptide ABC transporter, periplasmic peptide-binding protein; Similar to GB:Pyro_h; identified by sequence similarity; putative.
 
   
 0.824
VC_0616
Peptide ABC transporter, ATP-binding protein; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
       0.773
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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