Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0648Conserved hypothetical protein; May be involved in cell division. (303 aa)    
Predicted Functional Partners:
VC_1496
Tail-specific protease; Similar to GP:216618; identified by sequence similarity; putative.
  
 
 
 0.896
VC_1537
Lipoprotein NlpC; Similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788; identified by sequence similarity; putative.
    
 
 0.810
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.806
bamC
Lipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.793
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
   
 0.792
proQ
Conserved hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
   
 0.782
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.774
VC_2093
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
    0.770
VC_1099
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.769
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.766
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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