Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0665Sigma-54 dependent transcriptional regulator; Similar to GP:3236438; identified by sequence similarity; putative. (444 aa)    
Predicted Functional Partners:
VC_2529
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.794
VC_2067
MinD-related protein; Similar to GP:3695013; identified by sequence similarity; putative.
  
 
 0.770
VC_2748
Nitrogen regulation protein; Similar to SP:P19906 PID:155172; identified by sequence similarity; putative.
 
 
 0.756
lysS
lysyl-tRNA synthetase, heat inducible; Similar to GB:U14003 GB:J03795 SP:P13030 SP:P14825 GB:M30630; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.686
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
  
 
 0.558
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.537
VC_2198
Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
  
  
 0.505
fliE
Flagellar hook-basal body complex protein FliE; Similar to PID:2338730; identified by sequence similarity; putative.
  
  
 0.501
flhA
Flagellar biosynthetic protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.495
VC_1315
Sensor histidine kinase; Similar to SP:P26489 GB:X56658 GB:X59071 PID:38703 PID:38705; identified by sequence similarity; putative.
 
 
 0.493
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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