STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0667Oxidoreductase Tas, aldo/keto reductase family; Similar to PID:882727 GB:U00096 PID:1789199 PID:2342573; identified by sequence similarity; putative. (352 aa)    
Predicted Functional Partners:
VC_1849
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 
 0.801
VC_2299
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 
 0.801
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
   
 
 0.799
VC_A0788
DnaJ-related protein; Similar to SP:P48207 PID:893246; identified by sequence similarity; putative.
    
 
 0.794
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 
 
 0.794
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.779
VC_A0702
Iron-containing alcohol dehydrogenase; Similar to PID:882540 GB:U00096 PID:1789386; identified by sequence similarity; putative.
  
 
 0.700
VC_0244
Perosamine synthase; Similar to GB:X59554 PID:48386; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.677
VC_0745
Inositol monophosphate family protein; Similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882; identified by sequence similarity; putative; Belongs to the inositol monophosphatase superfamily.
   
 
 0.658
VC_1293
Aspartate aminotransferase; Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013; identified by sequence similarity; putative.
    
 
 0.656
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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