STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0687Carbon starvation protein A, putative; Similar to GP:3212213; identified by sequence similarity; putative. (494 aa)    
Predicted Functional Partners:
VC_A1071
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.727
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
  
  
 0.685
VC_1158
Hypothetical protein; Identified by Glimmer2; putative.
    
   0.650
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
   0.650
VC_A0667
Sodium/solute symporter; Similar to PID:1653432; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.628
acsA
acetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  
 0.616
VC_1340
prpE protein; Similar to GB:U00096 SP:P77495 PID:1657531 PID:1786529; identified by sequence similarity; putative.
   
  
 0.616
VC_A0829
acetyl-CoA synthase; Similar to GB:AE000782; identified by sequence similarity; putative.
   
  
 0.616
VC_A0628
SecA-related protein; Similar to GB:X79725 SP:P47994 PID:499335; identified by sequence similarity; putative.
    
   0.585
VC_0688
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.516
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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