STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
nspSSpermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein, putative; Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity. (359 aa)    
Predicted Functional Partners:
VC_1426
Spermidine/putrescine ABC transporter, permease protein; Similar to GB:M64519 SP:P23859 PID:147328 GB:U00096 PID:1651551; identified by sequence similarity; putative.
 
 0.968
VC_1427
Spermidine/putrescine ABC transporter, permease protein; Similar to GB:M64519 SP:P23860 PID:147327 GB:U00096 PID:1651552; identified by sequence similarity; putative.
 
 
 0.967
mbaA
c-di-GMP phosphodiesterase A-related protein; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels.
     
 0.948
potA
Spermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 
 
 0.944
VC_1425
Spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.
  
  
  0.906
VC_0702
Conserved hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
     
 0.847
fbpC
iron(III) ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
 
 
 0.794
VC_A0602
ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
 
 0.788
VC_0610
iron(III) ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
 
 0.735
VC_1424
Spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.
  
  
 
0.643
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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