Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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VC_0710Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the multicopper oxidase YfiH/RL5 family. (240 aa)    
Predicted Functional Partners:
VC_0585
Hypoxanthine phosphoribosyltransferase; Similar to SP:P18134 GB:X53382 PID:48439; identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
  0.922
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.906
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.906
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
  0.905
add
Adenosine deaminase; Similar to GB:M59033 SP:P22333 PID:145201 GB:U00096 PID:1742677; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
    
  0.904
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.902
VC_0899
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.902
VC_1129
Inosine-guanosine kinase; Similar to GB:D00798 SP:P22937 PID:216562 PID:520811 PID:216519; identified by sequence similarity; putative.
     
  0.900
nutA
UDP-sugar hydrolase; Degradation of extracellular 5'-nucleotides for nutritional needs.
     
  0.900
deoD1
Purine nucleoside phosphorylase; Similar to PID:1732037; identified by sequence similarity; putative.
     
  0.900
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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