Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0715NADPH-flavin oxidoreductase; Similar to GB:U08996 PID:478986; identified by sequence similarity; putative; Belongs to the flavin oxidoreductase frp family. (240 aa)    
Predicted Functional Partners:
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
  
  
  0.912
VC_0681
Riboflavin kinase/FMN adenylyltransferase; Similar to GB:U00096 PID:1786208; identified by sequence similarity; putative; Belongs to the ribF family.
    
 0.910
VC_0129
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.900
VC_0714
Hypothetical protein; Identified by Glimmer2; putative.
       0.845
VC_A0637
Oxygen-insensitive NAD(P)H nitroreductase; Similar to GB:M63808 SP:Q01234 PID:148362; identified by sequence similarity; putative.
      
 0.770
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.653
VC_0249
rfbL protein; Similar to GB:X59554 PID:48391; identified by sequence similarity; putative.
   
 
 0.638
VC_1971
O-succinylbenzoic acid--CoA ligase; Similar to GB:L35031 SP:P37353 PID:520813 GB:U00096 PID:1788595; identified by sequence similarity; putative.
   
 
 0.638
VC_1985
long-chain-fatty-acid--CoA ligase; Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096; identified by sequence similarity; putative.
   
 
 0.638
VC_0590
Permease, putative; Similar to GB:D26562 SP:P36880 PID:473795 GB:U00096 PID:1786320; identified by sequence similarity; putative.
  
  
 0.544
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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