STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0731Antioxidant, AhpC/Tsa family; Similar to PID:965473; identified by sequence similarity; putative. (207 aa)    
Predicted Functional Partners:
dsbE
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily.
  
 0.984
VC_2637
Peroxiredoxin family protein/glutaredoxin; Similar to GB:L42023 PID:1004026 PID:1222510 PID:1204821 SP:P44758; identified by sequence similarity; putative.
  
 0.963
trxB
Thioredoxin reductase; Similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096; identified by sequence similarity; putative.
  
 
 0.962
VC_1350
Antioxidant, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.914
VC_1585
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
  
 
 0.914
VC_0306
Thioredoxin; Similar to SP:P00274 GB:M87049 GB:K02845 GB:M10424 GB:M12779; identified by sequence similarity; putative; Belongs to the thioredoxin family.
  
 
 0.801
VC_0981
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.763
VC_0977
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.761
VC_A0752
Thioredoxin 2; Similar to SP:P33636 GB:U00096 PID:1788936 PID:1799987; identified by sequence similarity; putative.
  
 
 0.761
VC_0139
DPS family protein; Similar to GB:L42023 SP:P45173 PID:1007363 PID:1221482 PID:1205585; identified by sequence similarity; putative; Belongs to the Dps family.
  
  
 0.751
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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