Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
VC_0731Antioxidant, AhpC/Tsa family; Similar to PID:965473; identified by sequence similarity; putative. (207 aa)    
Predicted Functional Partners:
dsbE
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily.
  
 0.935
VC_2637
Peroxiredoxin family protein/glutaredoxin; Similar to GB:L42023 PID:1004026 PID:1222510 PID:1204821 SP:P44758; identified by sequence similarity; putative.
  
 0.934
trxB
Thioredoxin reductase; Similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096; identified by sequence similarity; putative.
  
 
 0.931
VC_1585
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
  
 
 0.900
VC_1583
Superoxide dismutase, Cu-Zn; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.889
VC_1350
Antioxidant, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.871
VC_2160
Bacterioferritin comigratory protein; Similar to GB:M63654 SP:P23480 PID:147017 GB:U00096 PID:1621502; identified by sequence similarity; putative.
 
 
 0.822
VC_0306
Thioredoxin; Similar to SP:P00274 GB:M87049 GB:K02845 GB:M10424 GB:M12779; identified by sequence similarity; putative; Belongs to the thioredoxin family.
  
 
 0.775
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.770
fur-2
Ferric uptake regulation protein; Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon.
  
  
 0.757
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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