Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pepBPeptidase B; Probably plays an important role in intracellular peptide degradation. (444 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Similar to SP:P04425 GB:X01666 PID:41625 PID:882476 GB:U00096; identified by sequence similarity; putative.
   
 
 0.933
VC_1494
Aminopeptidase N; Similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142; identified by sequence similarity; putative.
   
 0.932
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
  
  
0.924
VC_0194
Gamma-glutamyltranspeptidase; Similar to GB:AL123456; identified by sequence similarity; putative.
     
 0.912
VC_2279
Aminoacyl-histidine dipeptidase; Similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140; identified by sequence similarity; putative.
   
 
 0.911
VC_0754
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.908
gshA
Glutamate--cysteine ligase; Similar to SP:P06980 GB:X03954 PID:581100 GB:U00096 PID:1789044; identified by sequence similarity; putative; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.906
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
    
 0.845
VC_0968
Cysteine synthase A; Similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  0.824
VC_1061
Cysteine synthase/cystathionine beta-synthase family protein; Similar to GB:AL123456; identified by sequence similarity; putative.
   
  0.824
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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