STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (494 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438; identified by sequence similarity; putative.
  
 0.982
gpsA
Glycerol-3-phosphate dehydrogenase (NAD+); Similar to SP:P37606 PID:466746 GB:U00096 PID:1657692 PID:1790037; identified by sequence similarity; putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.948
rluB
Pseudouridine synthase family 1 protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.865
rsuA
Ribosomal small subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.799
VC_2744
GTP-binding protein TypA; Similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302; identified by sequence similarity; putative.
 
  
 0.775
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
 
  
 0.768
VC_0764
Hypothetical protein; Identified by Glimmer2; putative.
       0.743
engB
Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
 
   
 0.738
rluE
Pseudouridine synthase family 1 protein; Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.735
VC_2223
Pseudouridine synthase family 1 protein; Similar to SP:P32684 PID:396357 GB:U00096 PID:1790453; identified by sequence similarity; putative; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.711
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.