STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vibBVibriobactin-specific isochorismatase; Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm; Belongs to the isochorismatase family. (293 aa)    
Predicted Functional Partners:
vibE
Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase; Activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate, preparing that molecule for the final stages of vibriobactin synthesis.
 
 0.999
vibC
Vibriobactin-specific isochorismate synthase; Similar to PID:2182763; identified by sequence similarity; putative; Belongs to the isochorismate synthase family.
 
 
 0.999
VC_0775
Vibriobactin synthesis protein, putative; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
 
 
 0.999
VC_1579
Enterobactin synthetase component F-related protein; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
 
 0.999
menF
Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
 
 0.998
vibA
Vibriobactin-specific 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Involved in an early step of the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm.
 
 
 0.995
VC_0780
Vibriobactin synthase component D; Similar to SP:P19925 GB:U00096 PID:1651241 PID:1778499 PID:1786797; identified by sequence similarity; putative; Belongs to the P-Pant transferase superfamily.
 
  
 0.989
VC_0776
Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein; Similar to GB:M29730 SP:P14609 GB:X53274 PID:145944 PID:581195; identified by sequence similarity; putative.
 
  
 0.979
VC_0200
iron(III) compound receptor; Similar to GB:D26562 SP:P06971 GB:M12486 PID:145949 PID:473809; identified by sequence similarity; putative.
   
  
 0.957
viuB
Vibriobactin utilization protein ViuB; Involved in intracellular removal of iron from iron- vibriobactin complex. Vibriobactin is an iron-chelating compound involved in the transport of iron from the bacterial environment into the cell cytoplasm (By similarity); Belongs to the SIP oxidoreductase family.
 
  
 0.944
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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