STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0780Vibriobactin synthase component D; Similar to SP:P19925 GB:U00096 PID:1651241 PID:1778499 PID:1786797; identified by sequence similarity; putative; Belongs to the P-Pant transferase superfamily. (261 aa)    
Predicted Functional Partners:
vibB
Vibriobactin-specific isochorismatase; Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm; Belongs to the isochorismatase family.
 
 
 0.997
VC_0775
Vibriobactin synthesis protein, putative; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
 
 
 0.995
vibE
Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase; Activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate, preparing that molecule for the final stages of vibriobactin synthesis.
 
 
 0.958
VC_1579
Enterobactin synthetase component F-related protein; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
 
 
 0.861
VC_0776
Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein; Similar to GB:M29730 SP:P14609 GB:X53274 PID:145944 PID:581195; identified by sequence similarity; putative.
 
  
 0.824
vibA
Vibriobactin-specific 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Involved in an early step of the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm.
  
 
 0.819
VC_0779
Ferric vibriobactin ABC transporter, ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504; identified by sequence similarity; putative.
  
  
 0.796
VC_0781
Transcriptional regulator, LysR family; Similar to GB:D10483 SP:P10151 GB:M21150 PID:1128961 PID:146605; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
       0.762
vibC
Vibriobactin-specific isochorismate synthase; Similar to PID:2182763; identified by sequence similarity; putative; Belongs to the isochorismate synthase family.
 
  
 0.638
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
   
 
  0.613
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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