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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dadAD-amino acid dehydrogenase, small subunit; Oxidative deamination of D-amino acids. (421 aa)    
Predicted Functional Partners:
VC_1344
4-hydroxyphenylpyruvate dioxygenase; Similar to PID:2108220; identified by sequence similarity; putative.
   
 
 0.914
hisC
Histidinol-phosphate aminotransferase; Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710; identified by sequence similarity; putative; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.902
VC_1293
Aspartate aminotransferase; Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013; identified by sequence similarity; putative.
     
 0.902
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
     
 0.902
thiG
thiG protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.849
alr1
Alanine racemase, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan. To a lesser extent, is also able to racemize L-serine and D-serine. Does not act on other proteinogenic amino-acids.
  
 
 0.825
bsrV
Alanine racemase, putative; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Among these substrates, is the most efficient with lysine and arginine. Is also able to catalyze the racemization of several amino acids that are not typically incorporated into proteins such as ornithine and norleucine. Is not active on negatively charged (Glu and Asp) or aromati [...]
  
 
 0.825
VC_A0644
NADH oxidase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
   
 
 0.801
VC_0785
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
VC_0787
Transcriptional regulator, LysR family; Similar to SP:P46068 PID:1050466 GB:U00096 PID:1788706 PID:1799763; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
     
 0.751
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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