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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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tcpTToxin co-regulated pilus biosynthesis protein T; Involved in the translocation of the TcpA pilin. (503 aa)    
Predicted Functional Partners:
tcpE
Toxin co-regulated pilus biosynthesis protein E; Probably involved in cholera toxin receptor (GM1) interaction in order to bring the cells within close proximity of the ganglioside for efficient toxin delivery.
 
 
 0.974
pilC
Type IV pilin biogenesis protein PilC; Involved in the translocation of the type IV pilin; Belongs to the GSP F family.
 
 
 0.962
epsF
General secretion pathway protein F; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
 
 
 0.953
tcpJ
Leader peptidase TcpJ; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. Processes the TcpA pilin precursor during membrane translocation.
 
 
 0.952
VC_0406
MSHA biogenesis protein MshG; Similar to PID:1016255 PID:1016256; identified by sequence similarity; putative.
 
 
 0.947
tcpR
Toxin co-regulated pilus biosynthesis protein R; Involved in TCP pilus biogenesis.
   
 
 0.934
VC_2426
Leader peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.870
tcpS
Toxin co-regulated pilus biosynthesis protein S; The toxin coregulated pilus (TCP) is essential for successful colonization of the small intestine.
     
 0.861
tcpC
Toxin co-regulated pilus biosynthesis outer membrane protein C; Involved in TCP pilus biogenesis.
  
  
 0.858
tcpQ
Toxin co-regulated pilus biosynthesis protein Q; Involved in TCP pilus biogenesis.
     
 0.848
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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