STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0850Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0125 (RnfH) family. (103 aa)    
Predicted Functional Partners:
ratA
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes. Its antitoxin is unknown (By similarity).
 
  
 0.917
rnfB
RnfB-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
 
   
 0.797
rnfG
RnfG-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
 
  
 0.735
rnfD
RnfD-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
 
  
 0.706
rnfC
RnfC-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
 
  
 0.688
rnfE
RnfE-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.660
VC_0163
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.599
smpB
Small protein B; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tran [...]
       0.566
rnfA
RnfA-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
   
 0.548
VC_0459
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.545
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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