Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_0876Conserved hypothetical protein; Identified by Glimmer2; putative. (231 aa)    
Predicted Functional Partners:
rpmE2
Ribosomal protein, L31P family; Similar to GB:U00096 PID:1657496 PID:2367109; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
  
    0.746
rpmJ2
Ribosomal protein L36, putative; Similar to SP:P28528; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL36 family.
       0.741
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.696
VC_0881
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0178 family.
  
    0.503
VC_0872
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0253 family.
       0.487
VC_0882
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.478
VC_1260
Transcriptional regulator, AraC/XylS family; Similar to GP:2906236; identified by sequence similarity; putative.
      
 0.447
VC_A1107
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.447
VC_0862
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.435
VC_0992
Glutathione-regulated potassium-efflux system protein KefB, putative; Similar to SP:P52068 GB:U00096 PID:1773160 PID:1786685; identified by sequence similarity; putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
      
 0.435
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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