Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metIABC transporter, permease protein; Part of the binding-protein-dependent transport system for D- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (225 aa)    
Predicted Functional Partners:
metQ
Lipoprotein YaeC; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; Belongs to the NlpA lipoprotein family.
 0.999
metN
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.999
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
    0.785
gmhB
Histidinol phosphatase-related protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position in vitro. Also catalyzes the dephosphorylation of D-glycero-alpha-D-manno-heptose-1,7- bisphosphate in vitro; Belongs to the GmhB family.
       0.713
VC_0909
Trehalose operon repressor; Similar to SP:P36673 GB:U07790 PID:465107 PID:537083 GB:U00096; identified by sequence similarity; putative.
       0.661
VC_2195
Flagellar basal-body rod protein FlgG; Similar to GB:U00096 SP:P75939 PID:1787318; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
    
   0.577
VC_2685
5,10-methylenetetrahydrofolate reductase; Similar to GB:L19201 SP:P00394 GB:V01502 PID:305044 PID:42000; identified by sequence similarity; putative; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.519
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
   
  
 0.464
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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