Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_0910PTS system, trehalose-specific IIBC component; Similar to SP:P36672 GB:U06195 PID:459401 GB:U00096 PID:2367362; identified by sequence similarity; putative. (478 aa)    
Predicted Functional Partners:
VC_0964
PTS system, glucose-specific IIA component; Similar to GB:J02796 SP:P08837 GB:M93578 GB:M93579 GB:M93580; identified by sequence similarity; putative.
 0.999
VC_0911
Trehalose-6-phosphate hydrolase; Similar to SP:P39795 PID:580942 PID:1000452 GB:AL009126; identified by sequence similarity; putative.
 
 
 0.991
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.929
VC_0613
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
  
  
 0.921
VC_2217
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
  
  
 0.921
VC_A0655
Sucrose-6-phosphate dehydrogenase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.910
VC_1826
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
 
  
 0.877
VC_1822
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
 
  
 0.874
VC_0270
ROK family protein; Similar to SP:P23917 GB:X76979 PID:145329 PID:581151 GB:U00096; identified by sequence similarity; putative.
  
 
 0.839
VC_0993
N-acetylglucosamine repressor; Similar to GP:2541902; identified by sequence similarity; putative.
  
 
 0.839
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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