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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0947D-alanyl-D-alanine carboxypeptidase; Similar to SP:P04287 PID:146620 PID:147661 PID:41212 GB:U00096; identified by sequence similarity; putative; Belongs to the peptidase S11 family. (391 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.814
VC_0632
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Similar to GB:L42023 SP:P45161 PID:1007328 PID:1221461 PID:1205568; identified by sequence similarity; putative.
     
 0.803
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
  
 0.698
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
   
 0.679
mrcA
Penicillin-binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.645
VC_0344
N-acetylmuramoyl-L-alanine amidase; Similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010; identified by sequence similarity; putative.
  
 
 0.627
VC_A0270
D-alanyl-D-alanine carboxypeptidase; Similar to GB:L42023 SP:P44466 PID:1004158 PID:1221933 PID:1204287; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
  
  
0.619
rlpA
Rare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family.
     
 0.607
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
     
 0.605
VC_2421
ampD protein; Similar to GB:D26562 SP:P13016 GB:L28105 GB:X15237 PID:40908; identified by sequence similarity; putative.
  
  
 0.550
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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