STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (638 aa)    
Predicted Functional Partners:
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.999
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits) (By similarity).
 
 
 0.995
mrcA
Penicillin-binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
 0.991
VC_0947
D-alanyl-D-alanine carboxypeptidase; Similar to SP:P04287 PID:146620 PID:147661 PID:41212 GB:U00096; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
  
 
 0.985
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 0.982
VC_0416
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.969
ftsI
Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
  
0.954
VC_0415
Rod shape-determining protein MreB; Similar to SP:P13519 GB:M22055 PID:606191 PID:1128967 GB:U00096; identified by sequence similarity; putative.
 
 
 
 0.946
VC_A0270
D-alanyl-D-alanine carboxypeptidase; Similar to GB:L42023 SP:P44466 PID:1004158 PID:1221933 PID:1204287; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
  
 
 0.945
VC_0632
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Similar to GB:L42023 SP:P45161 PID:1007328 PID:1221461 PID:1205568; identified by sequence similarity; putative.
     
 0.922
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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