Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_0972Porin, putative; Similar to SP:P24305; identified by sequence similarity; putative. (349 aa)    
Predicted Functional Partners:
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
     
 0.920
VC_1854
Porin, putative; Similar to GP:3377759; identified by sequence similarity; putative.
     
 0.910
VC_A1008
Outer membrane protein, putative; Similar to PID:1658032; identified by sequence similarity; putative.
     
  0.900
VC_2213
Outer membrane protein OmpA; Similar to GP:2641145; identified by sequence similarity; putative; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 0.852
VC_2048
vacJ lipoprotein; Similar to GB:U00096 SP:P76506 PID:1788688 PID:1799744; identified by sequence similarity; putative.
   
 
 0.767
btuB
Vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
    
 0.764
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 
 0.755
VC_A0700
Chitodextrinase; Similar to GP:3928775; identified by sequence similarity; putative.
  
  
 0.746
VC_A0027
Chitinase; Similar to SP:P32823 PID:216207; identified by sequence similarity; putative.
  
  
 0.720
VC_0769
Chitinase, putative; Similar to SP:P08252 PID:19861 PID:19863 PID:512387; identified by sequence similarity; putative.
  
  
 0.717
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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