VC_0982 protein (Vibrio cholerae) - STRING interaction network

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Score

VC_0982

Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative. (97 aa)

Predicted Functional Partners:

toxS

0.792

toxR

0.792

htpG

0.681

Your Current Organism:

Vibrio cholerae

NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VC_0982	htpG	VC_0982	VC_0985	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	0.681
VC_0982	toxR	VC_0982	VC_0984	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	0.792
VC_0982	toxS	VC_0982	VC_0983	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	0.792
htpG	VC_0982	VC_0985	VC_0982	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	0.681
htpG	toxR	VC_0985	VC_0984	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	0.749
htpG	toxS	VC_0985	VC_0983	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	0.804
toxR	VC_0982	VC_0984	VC_0982	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	0.792
toxR	htpG	VC_0984	VC_0985	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	0.749
toxR	toxS	VC_0984	VC_0983	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	0.999
toxS	VC_0982	VC_0983	VC_0982	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	Selenoprotein W-related protein; Similar to SP:O19097; identified by sequence similarity; putative.	0.792
toxS	htpG	VC_0983	VC_0985	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.	0.804
toxS	toxR	VC_0983	VC_0984	Regulatory protein ToxS; Interacts with ToxR and stimulates its activity.	Cholera toxin transcriptional activator; This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.	0.999

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