node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glnS | proS | VC_0997 | VC_0875 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.965 |
glnS | rplD | VC_0997 | VC_2595 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | 0.966 |
glnS | rplF | VC_0997 | VC_2581 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.970 |
glnS | rplM | VC_0997 | VC_0570 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.968 |
glnS | rplO | VC_0997 | VC_2577 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.965 |
glnS | rplR | VC_0997 | VC_2580 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.970 |
glnS | rplV | VC_0997 | VC_2591 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.969 |
glnS | rplW | VC_0997 | VC_2594 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.975 |
glnS | rplX | VC_0997 | VC_2585 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.972 |
glnS | rpmD | VC_0997 | VC_2578 | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | Ribosomal protein L30; Similar to GB:L42023 SP:P44366 PID:1005798 PID:1220890 PID:1205044; identified by sequence similarity; putative. | 0.961 |
proS | glnS | VC_0875 | VC_0997 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | 0.965 |
rplD | glnS | VC_2595 | VC_0997 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | glutaminyl-tRNA synthetase; Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168; identified by sequence similarity; putative. | 0.966 |
rplD | rplF | VC_2595 | VC_2581 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.997 |
rplD | rplM | VC_2595 | VC_0570 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.997 |
rplD | rplO | VC_2595 | VC_2577 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.998 |
rplD | rplR | VC_2595 | VC_2580 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.998 |
rplD | rplV | VC_2595 | VC_2591 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.999 |
rplD | rplW | VC_2595 | VC_2594 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.999 |
rplD | rplX | VC_2595 | VC_2585 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.998 |
rplD | rpmD | VC_2595 | VC_2578 | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). As the V.cholerae S10 leader can be regulated in vitro by the E.coli L4 protein this suggests the endogenous protein controls its own S10 operon in a similar fashion. | Ribosomal protein L30; Similar to GB:L42023 SP:P44366 PID:1005798 PID:1220890 PID:1205044; identified by sequence similarity; putative. | 0.997 |