STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1008Sodium-type flagellar protein MotY; Similar to GB:U06949 SP:P46233 PID:497129; identified by sequence similarity; putative. (294 aa)    
Predicted Functional Partners:
tolB
tolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 0.916
VC_0893
Chemotaxis protein PomB; Similar to PID:2130949; identified by sequence similarity; putative.
  
 
 0.843
VC_A0659
Protein F-related protein; Similar to PID:2062640; identified by sequence similarity; putative.
  
  
  0.797
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
  
 
 0.784
skp
Outer membrane protein OmpH; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
  
 
 0.782
VC_0097
Flagellar protein FliL, putative; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
 
 
 0.771
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.770
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.762
VC_0725
Phosphate ABC transporter, permease protein; Similar to PID:633994 PID:1369911; identified by sequence similarity; putative.
     
 0.754
VC_2601
Sodium-type flagellar protein MotX; Similar to GB:U09005 SP:P40608 PID:507737; identified by sequence similarity; putative.
 
  
 0.740
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.