STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
VC_1061Cysteine synthase/cystathionine beta-synthase family protein; Similar to GB:AL123456; identified by sequence similarity; putative. (355 aa)    
Predicted Functional Partners:
VC_2649
Serine acetyltransferase; Similar to SP:P05796 GB:M15745 GB:M34333 PID:145676 PID:145694; identified by sequence similarity; putative.
  
 0.959
VC_2683
Cystathionine gamma-synthase; Similar to GB:L19201 SP:P00935 PID:146846 PID:305042 GB:U00096; identified by sequence similarity; putative.
  
 0.951
VC_0919
Serine acetyltransferase-related protein; Similar to GB: GB: GB: PID:1107505 PID:1184048; identified by sequence similarity; putative.
  
 0.931
VC_0923
Serine acetyltransferase-related protein; Similar to GB:AE000511 SP:P71405 PID:1518452 PID:2314370; identified by sequence similarity; putative.
  
 0.931
VC_1671
Cystathionine beta-lyase; Similar to GB:M12858 SP:P06721 PID:146824 PID:882537 PID:1789383; identified by sequence similarity; putative.
  
 0.919
cysJ
Sulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.906
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.900
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
    
 0.861
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.858
VC_1027
Molybdenum cofactor biosynthesis protein D; Similar to SP:P30748 PID:42011 GB:U00096 PID:1651357 PID:1787002; identified by sequence similarity; putative.
  
 0.852
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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