STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1068Transcriptional regulator, ArsR family; Similar to SP:P15905 GB:X16045 PID:42717; identified by sequence similarity; putative. (113 aa)    
Predicted Functional Partners:
VC_A1015
Na+/H+ antiporter; Similar to GP:3123728; identified by sequence similarity; putative.
  
  
 0.639
VC_1069
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:L07499 SP:P34918 PID:410113; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
     
 0.598
VC_1070
Phosphatase, putative; Similar to PID:2224838; identified by sequence similarity; putative.
       0.567
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.521
VC_1071
Transporter, putative; Similar to GP:3128308; identified by sequence similarity; putative.
     
 0.516
cobB
Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.499
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
     
 0.489
VC_1671
Cystathionine beta-lyase; Similar to GB:M12858 SP:P06721 PID:146824 PID:882537 PID:1789383; identified by sequence similarity; putative.
  
 
 0.477
copA
Cation transport ATPase, E1-E2 family; Involved in copper export.
 
  
 0.463
VC_A1019
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.462
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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