Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1076Transcriptional regulator, AraC/XylS family; Similar to GB:U00096 SP:P77634 PID:1778460 PID:1786758; identified by sequence similarity; putative. (279 aa)    
Predicted Functional Partners:
VC_1075
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
    0.862
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.630
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.471
VC_0769
Chitinase, putative; Similar to SP:P08252 PID:19861 PID:19863 PID:512387; identified by sequence similarity; putative.
  
     0.464
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.460
VC_A0447
Haemagglutinin associated protein; Similar to GB:X64387 PID:396849 PID:48357; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family.
    
   0.460
VC_1888
Hemolysin-related protein; Similar to SP:P09545 GB:M36855 GB:X51746 PID:1136779 PID:155182; identified by sequence similarity; putative.
  
   
 0.425
VC_0930
Hemolysin-related protein; Similar to SP:P09545 GB:M36855 GB:X51746 PID:1136779 PID:155182; identified by sequence similarity; putative.
  
     0.414
VC_1074
Hypothetical protein; Identified by Glimmer2; putative.
       0.408
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.