Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_1089Periplasmic binding protein-related protein; Similar to SP:P16682 GB:U14003 PID:147197 PID:216592 PID:536949; identified by sequence similarity; putative. (270 aa)    
Predicted Functional Partners:
VC_1088
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874; identified by sequence similarity; putative.
 
     0.897
VC_1090
Hypothetical protein; Identified by Glimmer2; putative.
       0.701
VC_A0812
Leucine aminopeptidase-related protein; Similar to PID:1694931; identified by sequence similarity; putative.
   
    0.679
VC_0725
Phosphate ABC transporter, permease protein; Similar to PID:633994 PID:1369911; identified by sequence similarity; putative.
   
  
 0.459
VC_0727
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
   
  
 0.456
VC_1652
Response regulator VieA; Similar to GP:3123891; identified by sequence similarity; putative.
  
  
 0.431
hisF
Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
   
  
 0.420
VC_A0033
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.412
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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