Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1157Response regulator; Similar to PID:643672; identified by sequence similarity; putative. (256 aa)    
Predicted Functional Partners:
VC_1156
Sensor histidine kinase; Similar to GP:2655263; identified by sequence similarity; putative.
 
 
 0.971
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
  
 
 0.904
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
  
 
 0.888
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
  
 
 0.888
VC_1653
Sensory box sensor histidine kinase/response regulator VieS; Similar to GP:3123890; identified by sequence similarity; putative.
  
 
 0.827
VC_1155
Response regulator; Similar to GP:551953; identified by sequence similarity; putative.
 
   
0.826
cqsS
Sensor histidine kinase/response regulator LuxN; Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to LuxU and LuxO.
 
 
 0.815
VC_0901
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 
 0.782
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
   0.779
VC_0425
Hypothetical protein; Identified by Glimmer2; putative.
  
   
 0.776
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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