Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trxBThioredoxin reductase; Similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096; identified by sequence similarity; putative. (318 aa)    
Predicted Functional Partners:
VC_0306
Thioredoxin; Similar to SP:P00274 GB:M87049 GB:K02845 GB:M10424 GB:M12779; identified by sequence similarity; putative; Belongs to the thioredoxin family.
 
 0.995
VC_A0752
Thioredoxin 2; Similar to SP:P33636 GB:U00096 PID:1788936 PID:1799987; identified by sequence similarity; putative.
 
 0.934
VC_0731
Antioxidant, AhpC/Tsa family; Similar to PID:965473; identified by sequence similarity; putative.
  
 
 0.931
dsbE
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily.
  
 
 0.845
VC_0977
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.833
VC_A0924
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.777
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.722
VC_1254
Iron-sulfur cluster-binding protein, putative; Similar to GB:L42023 SP:P45154 PID:1007287 PID:1221440 PID:1205547; identified by sequence similarity; putative.
   
 
 0.717
VC_0186
Glutathione reductase; Similar to SP:P06715 GB:M13141 PID:146248 PID:466637 GB:U00096; identified by sequence similarity; putative.
  
 
 0.712
VC_0753
Ferredoxin; Similar to GB:M88654 SP:P25528 PID:145915 GB:U00096 PID:1788874; identified by sequence similarity; putative.
   
 
 0.707
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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