Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1206Histidine utilization repressor; Similar to GB:M33922 SP:P22773 PID:151276; identified by sequence similarity; putative. (236 aa)    
Predicted Functional Partners:
hutI
Imidazolonepropionase; Similar to SP:P42084 PID:603768 GB:AL009126; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.959
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.951
hutH
Histidine ammonia-lyase; Similar to GB:M35140 SP:P21310 PID:151274; identified by sequence similarity; putative; Belongs to the PAL/histidase family.
 
  
 0.940
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.815
ectC
Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
  
  
 0.626
VC_1486
ABC transporter, ATP-binding protein; Similar to SP:P43673 GB:U00096 PID:1787182 PID:2251144; identified by sequence similarity; putative.
      
 0.554
fadR
Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism.
   
  
 0.541
hutZ
Conserved hypothetical protein; Involved in heme degradation. Catalyzes the degradation of heme to biliverdin, with the release of iron. Forms biliverdin beta and delta. Binds heme with high efficiency.
      
 0.539
VC_1207
Hypothetical protein; Identified by Glimmer2; putative.
       0.535
VC_2415
Pyruvate dehydrogenase complex repressor; Similar to PID:455922 GB:U00096 SP:P06957 PID:1786303 PID:434009; identified by sequence similarity; putative.
  
  
 0.529
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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