STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1224Hypothetical protein; Identified by Glimmer2; putative. (259 aa)    
Predicted Functional Partners:
VC_1543
Hypothetical protein; Identified by Glimmer2; putative.
  
  
  0.786
VC_1367
GGDEF family protein; Similar to PID:633121; identified by sequence similarity; putative.
  
 
  0.776
VC_1223
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
VC_A0592
MutT/nudix family protein; Similar to SP:P46351; identified by sequence similarity; putative.
 
  
  0.768
VC_1505
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.767
mnmE
Thiophene and furan oxidation protein ThdF; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.754
VC_A0785
GGDEF family protein; Similar to PID:1651932; identified by sequence similarity; putative.
    
  0.753
VC_0904
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.751
VC_A0931
Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade other cGAMP linkage isomers (3'2'-, 2'3'-, and 2'2'-cGAMPs); is also able to hydr [...]
   
 
  0.751
VC_A0059
Major outer membrane lipoprotein; Similar to GB:M13176 SP:P09461 GB:M28554 PID:150894 PID:150896; identified by sequence similarity; putative.
  
     0.739
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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