STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1235Sodium/dicarboxylate symporter; Similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024; identified by sequence similarity; putative; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (471 aa)    
Predicted Functional Partners:
VC_2195
Flagellar basal-body rod protein FlgG; Similar to GB:U00096 SP:P75939 PID:1787318; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
    
   0.693
cysJ
Sulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
  
 0.636
VC_2523
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
   0.622
cysD
Sulfate adenylate transferase, subunit 2; Similar to GB:M74586 SP:P21156 PID:145669 PID:145672 PID:882645; identified by sequence similarity; putative.
   
  
 0.617
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
    0.610
VC_0538
Thiosulfate ABC transporter, periplasmic thiosulfate-binding protein; Similar to GB:M32101 SP:P16700 PID:145658 GB:U00096 PID:1788765; identified by sequence similarity; putative.
   
    0.605
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
    0.590
cysN
Sulfate adenylate transferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
    0.588
VC_1234
Similar to SP:P04995 GB:J02641 GB:U00009 PID:405954 PID:147788; identified by sequence similarity; putative.
       0.537
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
   
  
 0.515
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.