Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
btuCVitamin B12 ABC transporter, permease protein BtuC, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (335 aa)    
Predicted Functional Partners:
btuD
Vitamin B12 ABC transporter, ATP-binding protein BtuD, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
 
 
 0.999
btuF
Conserved hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
 
 0.998
hmuV
Hemin ABC transporter, ATP-binding protein HutD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
  
   
 0.846
VC_0202
iron(III) ABC transporter, periplasmic iron-compound-binding protein; Similar to GB:D26562 SP:P07822 GB:M12486 PID:145951 PID:41441; identified by sequence similarity; putative.
 
 
 
 0.836
VC_0201
iron(III) ABC transporter, ATP-binding protein; Similar to PID:41440 GB:U00096 PID:1552729 PID:1786345; identified by sequence similarity; putative.
 
   
 0.795
VC_0779
Ferric vibriobactin ABC transporter, ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504; identified by sequence similarity; putative.
 
   
 0.789
VC_A0913
Hemin ABC transporter, periplasmic hemin-binding protein HutB; Similar to GP:2738773; identified by sequence similarity; putative.
  
   
 0.762
astE
Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
       0.761
VC_A0230
iron(III) ABC transporter, ATP-binding protein; Similar to GB:AL009126; identified by sequence similarity; putative.
 
     0.750
VC_1240
Alpha-ribazole-5`-phosphate phosphatase CobC, putative; Similar to PID:727431 SP:P52086 GB:U00096 PID:1778556 PID:1786857; identified by sequence similarity; putative.
     
 0.638
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]