STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1291Conserved hypothetical protein; Identified by Glimmer2; putative. (637 aa)    
Predicted Functional Partners:
VC_1290
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
 
    0.969
VC_0299
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000657; identified by sequence similarity; putative.
 
    0.904
VC_2705
Sodium/solute symporter, putative; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.895
VC_2704
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.660
VC_1655
Magnesium transporter; Acts as a magnesium transporter.
     
 0.556
VC_A0986
Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.502
VC_1817
Sigma-54 dependent transcriptional regulator; Similar to GB:M90471 SP:P28614 PID:141888; identified by sequence similarity; putative.
   
  
 0.501
VC_1067
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.483
VC_1292
Hypothetical protein; Identified by Glimmer2; putative.
       0.483
purR
Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
      
 0.415
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.