STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1291Conserved hypothetical protein; Identified by Glimmer2; putative. (637 aa)    
Predicted Functional Partners:
VC_1290
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
 
 
  0.968
VC_0299
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000657; identified by sequence similarity; putative.
 
 
  0.909
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.866
VC_2705
Sodium/solute symporter, putative; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.866
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
 
  
 0.835
VC_2373
Glutamate synthase, large subunit; Similar to GB:X80485 PID:515938 SP:P55037 PID:1652093; identified by sequence similarity; putative.
    
 0.814
VC_2376
Glutamate synthase, large subunit; Similar to PID:606151 GB:U00096 PID:1789605; identified by sequence similarity; putative.
    
 0.814
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.812
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
    
  0.806
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
    
 0.769
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.