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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1321Hypothetical protein; Identified by Glimmer2; putative. (1023 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
   
 0.849
ftsI
Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
   
 0.849
VC_2676
Cell division protein FtsN, putative; Similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036; identified by sequence similarity; putative.
   
 
 0.837
VC_1894
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 
 0.777
VC_0283
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.704
VC_0344
N-acetylmuramoyl-L-alanine amidase; Similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010; identified by sequence similarity; putative.
  
 0.662
mrcA
Penicillin-binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
   
 0.662
VC_2153
D,D-carboxypeptidase-related protein; Similar to GB:L42023 SP:P43941 PID:1003104 PID:1222012 PID:1204359; identified by sequence similarity; putative.
     
 0.534
vgrG3
vgrG protein; Part of the type VI secretion system specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection. Forms the spike at the tip of the elongating tube formed by haemolysin co-regulated protein Hcp. Allows the delivery of the TseL antibacterial toxin to target cells where it exerts its toxicity. Additionally, acts directly as an effector and targets the cell wall peptidoglycan layer of prey cells for degradation via its C-terminus. Toxicity is counteracted by a cognate immunity protein TsiV3.
     
 0.531
VC_1417
Hypothetical protein; Identified by Glimmer2; putative.
   
  0.501
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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