Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1339Conserved hypothetical protein; Identified by Glimmer2; putative. (400 aa)    
Predicted Functional Partners:
VC_1338
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.999
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage reaction of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
 
  
 0.950
VC_1337
Methylcitrate synthase; Similar to GB:U00096 PID:1657529 PID:1786527; identified by sequence similarity; putative; Belongs to the citrate synthase family.
 
  
 0.913
VC_0604
Aconitate hydratase 2; Similar to SP:P36683 GB:U00096 PID:2367097; identified by sequence similarity; putative; Belongs to the aconitase/IPM isomerase family.
    
 0.912
VC_1340
prpE protein; Similar to GB:U00096 SP:P77495 PID:1657531 PID:1786529; identified by sequence similarity; putative.
  
  
 0.870
VC_1335
Transcriptional regulator, GntR family; Similar to GB:U00096 PID:1787821; identified by sequence similarity; putative.
 
  
 0.809
VC_1341
Acetyltransferase, putative; Similar to PID:1550710 GB:AL123456; identified by sequence similarity; putative.
       0.710
VC_2092
Citrate synthase; Similar to GB:J01619 SP:P00891 GB:M28987 GB:M28988 GB:V01501; identified by sequence similarity; putative; Belongs to the citrate synthase family.
  
  
 0.542
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
   0.512
VC_0050
DNA topoisomerase I-related protein; Similar to SP:P45771 PID:606217 GB:U00096 PID:1789677; identified by sequence similarity; putative.
   
    0.439
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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