Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
VC_1408Transcriptional regulator, TetR family; Similar to GB:M97208 SP:P32398 PID:143046 PID:2226233 GB:AL009126; identified by sequence similarity; putative. (200 aa)    
Predicted Functional Partners:
VC_1410
Multidrug resistance protein VceA; Similar to GP:3378278; identified by sequence similarity; putative.
 
   
 0.776
VC_1409
Multidrug resistance protein, putative; Similar to GP:3378279; identified by sequence similarity; putative.
 
   
 0.698
VC_1411
Multidrug resistance protein VceB; Similar to GP:2815578; identified by sequence similarity; putative; Belongs to the major facilitator superfamily.
 
     0.683
VC_A0792
Transposase OrfAB, subunit A; Similar to SP:P39213; identified by sequence similarity; putative.
      
 0.573
VC_A0767
Transcriptional regulator, TetR family; Similar to SP:P34000 GB:U00734 PID:532309 GB:U00096 PID:1773146; identified by sequence similarity; putative.
      
 0.552
VC_0781
Transcriptional regulator, LysR family; Similar to GB:D10483 SP:P10151 GB:M21150 PID:1128961 PID:146605; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
 
 
 0.500
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.468
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.450
VC_0256
Transposase OrfAB, subunit A; Similar to SP:P39213; identified by sequence similarity; putative.
      
 0.425
VC_1184
NifS-related protein; Similar to GB:U00096 PID:1742766 PID:1742773 PID:1787970; identified by sequence similarity; putative.
  
   
 0.407
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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