Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1436FixS-related protein; Similar to PID:2398785; identified by sequence similarity; putative. (54 aa)    
Predicted Functional Partners:
VC_1438
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.959
VC_1437
Cation transport ATPase, E1-E2 family; Similar to PID:1200219; identified by sequence similarity; putative.
 
  
 0.945
VC_1435
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.943
VC_1439
Cytochrome c oxidase, subunit CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
  
 0.930
VC_1441
Cytochrome c oxidase, subunit CcoO; Similar to PID:1377866; identified by sequence similarity; putative.
 
  
 0.918
VC_1442
Cytochrome c oxidase, subunit CcoN; Similar to SP:P98059 PID:556813; identified by sequence similarity; putative; Belongs to the heme-copper respiratory oxidase family.
 
   
 0.904
VC_1440
Cytochrome c oxidase, subunit CcoQ; Similar to PID:1377867; identified by sequence similarity; putative.
 
  
 0.892
fnr
Fumarate and nitrate reduction regulatory protein; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
  
  
 0.754
VC_0036
FixG-related protein; Similar to PID:2398782; identified by sequence similarity; putative.
 
  
 0.739
VC_1443
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.685
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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