Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1446Toxin secretion transporter, putative; Similar to SP:P16532 GB:M24197 PID:150495 PID:150514; identified by sequence similarity; putative. (721 aa)    
Predicted Functional Partners:
VC_1447
RTX toxin transporter; Similar to GP:4455068; identified by sequence similarity; putative.
 
 
 0.991
VC_A1080
Secretion protein, HlyD family; Similar to GP:1314576; identified by sequence similarity; putative.
 
 
 0.906
pstB2
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
0.900
VC_1448
RTX toxin transporter; Similar to GP:4455067; identified by sequence similarity; putative.
 
  
 
0.894
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
 
  
 0.784
VC_1607
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.762
viuB
Vibriobactin utilization protein ViuB; Involved in intracellular removal of iron from iron- vibriobactin complex. Vibriobactin is an iron-chelating compound involved in the transport of iron from the bacterial environment into the cell cytoplasm (By similarity); Belongs to the SIP oxidoreductase family.
   
   0.730
VC_1410
Multidrug resistance protein VceA; Similar to GP:3378278; identified by sequence similarity; putative.
  
 
 0.727
VC_1659
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.727
VC_A0047
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.727
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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